Alec J. Batts
Alumni
Academic Qualifications
- Ph.D., Biomedical Engineering, Columbia University (New York, NY, USA), Oct. 2024
- M.Phil., Biomedical Engineering, Columbia University (New York, NY, USA), Feb. 2024
- M.S., Biomedical Engineering, Columbia University (New York, NY, USA), Feb. 2021
- B.S., Biomedical Engineering, University of Virginia (Charlottesville, VA, USA), May 2019
Biography
Alec is from Jupiter, FL and received his bachelor’s degree in Biomedical Engineering at the University of Virginia in 2019. During his undergraduate career, Alec investigated the effects of focused ultrasound hyperthermia and microbubble cavitation on the secretion, proteomic profile and anti-tumor immunogenicity of cancer-derived extracellular vesicles under the guidance of Dr. Richard Price. Alec joined UEIL as an M.S./Ph.D candidate in the summer of 2019 and is currently developing novel platforms for focused ultrasound-mediated blood-brain barrier opening and drug delivery to enable more effective and accessible treatment of neurological disorders.
Awards
- Bernard Jaffe Prize for the Encouragement of Inventiveness in Engineering, 2025, Columbia University
- Yuen-huo Hung and Chao-chin Huang Graduate Award in Biomedical Engineering, 2025, Columbia University
- Student Poster Competition Award Winner - Ultrasonics, 2024 Ultrasonics, Ferroelectrics, and Frequency Control Joint Symposium (UFFC-JS) 2024, Taipei, Taiwan
- Student Award, 22nd Annual International Symposium for Therapeutic Ultrasound (ISTU) 2023, Lyon, France
- Student Award, 20th Annual International Symposium for Therapeutic Ultrasound (ISTU) 2021, Gyeongju, Korea
Publications
Response of Serum-Isolated Extracellular Vesicles to Focused Ultrasound-Mediated Blood-Brain Barrier Opening
Alina R. Kline-Schoder
Fotios N. Tsitsos
Alec J. Batts
Melody R. DiBenedetto
Keyu Liu
Sua Bae
Elisa E. Konofagou
Portable transcranial therapeutic ultrasound enhances targeted gene delivery for Parkinson's disease: from rodent models to non-human primates
Alec J. Batts
Robin Ji
Sua Bae
Fotis N. Tsitsos
Sergio Jimenez-Gambin
Nancy Kwon
Samantha L. Gorman
Deny Tsakri
Rebecca L. Noel
Jonas Bendig
Daniella A. Jimenez
Melody DiBenedetto
Sofia A. Del Castillo
Filimon B. Keleta
James Caicedo
Alexander Romanov
Colleen T. Curley
Yulia Dzhashiashvili
Greglynn D. Walton-Gibbs
Bradley S. Hollidge
Serge Przedborski
Elizabeth Ramsburg
Olivier Danos
Vincent P. Ferrera
Esteban A. Engel
Jared B. Smith
Elisa E. Konofagou
Transcranial blood-brain barrier opening in Alzheimer's disease patients using a portable focused ultrasound system with real-time 2-D cavitation mapping
Sua Bae
Keyu Liu
Antonios N. Pouliopoulos
Robin Ji
Sergio Jiménez-Gambín
Omid Yousefian
Alina R. Kline-Schoder
Alec J. Batts
Fotios N. Tsitsos
Danae Kokossis
Akiva Mintz
Lawrence S. Honig
Elisa E. Konofagou
Characterization of the responses of brain macrophages to focused ultrasound-mediated blood–brain barrier opening
Alina R. Kline-Schoder
Sana Chintamen
Moshe J. Willner
Melody R. DiBenedetto
Rebecca L. Noel
Alec J. Batts
Nancy Kwon
Stergios Zacharoulis
Cheng-Chia Wu
Vilas Menon
Steven G. Kernie
Elisa E. Konofagou
Using a novel rapid alternating steering angles pulse sequence to evaluate the impact of theranostic ultrasound-mediated ultra-short pulse length on blood-brain barrier opening volume and closure, cavitation mapping, drug delivery feasibility, and safety
Alec J. Batts
Robin Ji
Rebecca L. Noel
Alina R. Kline-Schoder
Sua Bae
Nancy Kwon
Elisa E. Konofagou
Getting ahead of Alzheimer's Disease: Early intervention with focused ultrasound
Rebecca L. Noel
Samantha L. Gorman
Alec J. Batts
Elisa E. Konofagou
Natural aging and Alzheimer’s disease pathology increase susceptibility to focused ultrasound-induced blood–brain barrier opening
Rebecca L. Noel
Alec J. Batts
Robin Ji
Antonios N. Pouliopoulos
Sua Bae
Alina R. Kline-Schoder
Elisa E. Konofagou
Non-invasive optogenetics with ultrasound-mediated gene delivery and red-light excitation
Antonios N. Pouliopoulos
Maria F. Murillo
Rebecca L. Noel
Alec J. Batts
Robin Ji
Nancy Kwon
Han Yu
Chi-Kun Tong
Jennifer N. Gelinas
Dion Khodagholy Araghy
S. Abid Hussaini
Elisa E. Konofagou
Transcranial Theranostic Ultrasound for Pre-Planning and Blood-Brain Barrier Opening: A Feasibility Study using an Imaging Phased Array in Vitro and in Vivo
Alec J. Batts
Robin Ji
Alina R. Kline-Schoder
Rebecca L. Noel
Elisa E. Konofagou
Conference abstracts and proceedings
CSHL Brain Barriers: Clinically relevant FUS-BBBO increases the extent of the opening volume and microglial activation compared to pre-clinical parameters
Daniella A. Jimenez
Sua Bae
Alec J. Batts
Fotios N. Tsitsos
Rashell K. Ramirez
Elisa E. Konofagou
IUS 2024: Non-Invasive Adeno-Associated Viral Gene Delivery to the Brain in Non-Human Primates with Cavitation-Guided Focused Ultrasound
Alec J. Batts
Robin Ji
Sua Bae
Sergio Jimenez Gambin
Fotios N. Tsitsos
Nancy Kwon
Vincent P. Ferrera
Jared B. Smith
Elisa E. Konofagou
IUS 2024: Non-Invasive Gene Delivery to Brain Lymphatic System Using an Imaging Phased Array and Ultra-Short Focused Ultrasound Pulses
Fotios N. Tsitsos
Alec J. Batts
Daniella A. Jimenez
Nancy Kwon
Samantha L. Gorman
Rashell K. Ramirez
Hadrien D. Padilla
Konstantina Kaplani
Maria Kanellopoulou
Stavros Taraviras
Elisa E. Konofagou
ISTU 2024: Non-Invasive Delivery of Adeno-Associated Viral Vectors to the Brain in Non-Human Primates with Theranostic Ultrasound
Alec J. Batts
Robin Ji
Sergio Jimenez Gambin
Fotios N. Tsitsos
Nancy Kwon
Vincent P. Ferrera
Elisa E. Konofagou
ISTU 2024: Characterization of microbubble cavitation in transcranial theranostic ultrasound-mediated blood-brain barrier opening
Fotios N. Tsitsos
Chunqi Li
Sua Bae
Alec J. Batts
Elisa E. Konofagou
AD/PD 2024: Non-invasive and targeted viral vector-mediated neurotrophic factor delivery to the brain with theranostic ultrasound induces neurorestorative effects in a Parkinson’s disease mouse model
Alec J. Batts
Samantha L. Gorman
Rebecca L. Noel
Daniella Jimenez
Fotis Tsitsos
Jonas Bendig
Filimon Keleta
Melody DiBenedetto
James Caicedo
Robin Ji
Nancy Kwon
Serge Przedborski
Elisa E. Konofagou
IUS 2023: Combination of lateral beam steering and axial focusing significantly increases theranostic ultrasound mediated blood-brain barrier opening volume and viral gene delivery in vivo
Alec J. Batts
Fotios N. Tsitsos
Samantha L. Gorman
Rebecca L. Noel
Robin Ji
Nancy Kwon
Elisa E. Konofagou
ISTU 2023: Theranostic ultrasound-facilitated magnetogenetics
Alec J. Batts
Madhuvanthi Kannan
Ganesh Vasan
Daniel T. Hinojosa
Rebecca L. Noel
Jeannette Ingabire
Nancy Kwon
Vincent A. Pieribone
Qingbo Zhang
Jacob T. Robinson
Elisa E. Konofagou
ACNP 2022: Theranostic Ultrasound-Mediated Blood-Brain Barrier Opening and Viral Gene Delivery With a Short-Pulse Sequence
Alec J. Batts
Elisa E. Konofagou
IUS 2022: Effect of pulse length on neuro-immune response after short-pulse theranostic ultrasound-mediated blood-brain barrier opening
Alec J. Batts
Rebecca L. Noel
Alina R. Kline-Schoder
Robin Ji
Elisa E. Konofagou
ISTU 2022: Theranostic ultrasound-mediated blood-brain barrier opening and viral gene delivery with a short pulse sequence
Alec J. Batts
Robin Ji
Rebecca L. Noel
Alina R. Kline-Schoder
Nancy Kwon
Elisa E. Konofagou
The Effect of Pulse Length on Theranostic Ultrasound-Mediated Blood-Brain Barrier Opening Volume, Closing Timeline, and Cavitation Mapping in Vivo
Alec Batts
Robin Ji
Rebecca L. Noel
Alina R. Kline-Schoder
Elisa Konofagou
IUS 2021: The Effect of Pulse Length on Opening Volume and Reversibility of Theranostic Ultrasound-Mediated Blood-Brain Barrier Opening in Vivo
Alec J. Batts
Robin Ji
Rebecca L. Noel
Elisa E. Konofagou
ISTU 2021: Transcranial Theranostic Ultrasound Pre-Planning and Blood-Brain Barrier Opening Using a Phased Array In Vitro and In Vivo
Alec Batts
Robin Ji
Alina Kline-Schoder
Rebecca Noel
Elisa E Konofagou
FUSF 2020: High resolution CT– based preplanning for transcranial blood-brain barrier opening
Alec J. Batts
Robin Ji
Alina Kline-Schoder
Rebecca Noel
Elisa Konofagou
Targeting accuracy of transcranial power cavitation imaging for blood-brain barrier opening using a theranostic phased array
Alec J. Batts
Elisa E. Konofagou