Welcome to the UEIL
Led by Prof. Elisa Konofagou, the Ultrasound Elasticity and Imaging Laboratory works on developing novel, ultrasound-based techniques for both imaging and therapeutic applications. Some of the ongoing research in the UEIL includes:
Enabling targeted drug delivery to the brain by opening the blood-brain barrier with focused ultrasound.
Mapping the mechanical and electromechanical properties of the heart using myocardial elastography and electromechanical wave imaging.
Monitoring High-Intensity Focused Ultrasound (HIFU) ablation therapy with harmonic motion imaging.
Using pulse wave imaging to quantify the stiffness of the arterial wall and assess the likelihood of an aneurysm rupturing.
Modulating neural activity in the central and peripheral nervous system through high-intensity focused ultrasound.
The UEIL is located in the Columbia University Medical Center at the New York Presbyterian Hospital and is part of the Department of Biomedical Engineering at Columbia University. If you have any additional inquiries, or if you would be interested in collaborating with our laboratory, please feel free to contact us.
We are excited to see our work on Electromechanical Wave imaging showcased in a Science Highlights article on the NIH website. The article gives a concise overview of the technique and summarizes some of our latest findings using EWI to localize the source of arrhythmias compared to 12-lead ECG. The full article can be found here.
The IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control (January 2021, Volume 68, Issue 1) featured our paper on Real-Time Passive Acoustic Mapping on the issue front cover. The paper describes an exciting, computationally efficient method of passive acoustic mapping using GPU-accelerated sparse matrix multiplication.
Elisa Konofagou, PhD, the Robert and Margaret Hariri Professor of Biomedical Engineering and Radiology at Columbia University, and her research team recently treated the first patient in their clinical trial to open the blood-brain barrier (BBB) in patients with Alzheimer’s disease. Read more about it here.