Rebecca Lynn Noel

Ph.D. Student

Academic Qualifications

  • M.Phil., Biomedical Engineering, Columbia University (New York, NY, USA), Feb 2023
  • M.S., Biomedical Engineering, Columbia University (New York, NY, USA), Feb 2021
  • B.S., Biological Engineering, Minor in Brain and Cognitive Sciences, Massachusetts Institute of Technology (Cambridge, MA, USA), June 2019

Biography

Rebecca grew up in Burlington, CT and completed her undergraduate career at the Massachusetts Institute of Technology in Cambridge, MA, where she earned her Bachelor’s degree in Biological Engineering with a minor in Brain and Cognitive Sciences. Rebecca’s undergraduate research focused on the development of a tissue culture platform for threedimensional in vitro modeling of the central nervous system. Rebecca also worked as an intern at Biogen in Cambridge, MA supporting the translational cell sciences team by expanding their in vitro Blood Brain Barrier (BBB) modeling capabilities through bioprinting for drug screening applications. Additionally, Rebecca worked as a research intern at the Institut du Cerveau et de la Moelle Épinière (Institute for Brain and Spinal Cord) in Paris studying patterns and routes of meningeal lymphatic clearance.

Rebecca is a Biomedical Engineering student in Columbia’s School of Engineering and Applied Sciences on the M.S. to Ph.D. track, and she joined the BBB team at UEIL in August 2019. Her work is implicated broadly in the characterization of focused ultrasound (FUS)-augmented drug delivery in neurodegenerative disease, and focuses specifically on the investigation of FUS in murine models of Alzheimer’s Disease.

Publications

Peer-reviewed articles

Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons

Lorena Galan-Acosta
Carlos Sierra
Axel Leppert
Antonios N. Pouliopoulos
Nancy Kwon
Rebecca L. Noel
Simone Tambaro
Jenny Presto
Per J. Nilsson
Elisa E. Konofagou
Jan Ove Johansson

Conference abstracts and proceedings

IUS 2020: Targeted Blood-Brain Barrier Opening by Focused Ultrasound Improves Spatial Memory in Wild Type Mice

Rebecca Noel
Maria Eleni Karakatsani
Maria Murillo
Alina Kline-Schoder
Robin Ji
Alec Batts
Antonios Pouliopoulos
Elisa Konofagou